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Epistasis is the interaction between two non-allelic genes where the phenotypic expression of one gene is masked or suppressed by the expression of one or more other genes. Earlier, Mendelian and his coworkers。

We assessed the functional impact of the epistasis signals across a range of functional/-omics datasets identifying significant single-variant eQTLs across brain tissues,。

Epistasis occurs when the phenotype expression of one gene is influenced by another gene. Example: Gene A must be present for Gene B to express a certain trait. Example: The coat color in mice is a classic example。

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